Cell division is not perfect. As we get older, mutations often appear in genes in normal cells. Most of these mutated cells and their progeny—called "somatic clones"—have no effect on our health, but a tiny fraction can help trigger cancer growth or contribute to other conditions such as cardiovascular disease. A team led by scientists from the Broad Institute's Cancer Program and Massachusetts General Hospital (MGH) has now created a powerful new approach that detects mutations across many different types of normal cells by analyzing RNA sequencing data from normal tissues.
* This article was originally published here
