FDA widens warning for contaminated eye products

The U.S. Food and Drug Administration (FDA) issued a warning to consumers Wednesday to stop buying and using Delsam Pharma's Artificial Eye Ointment due to potentially serious health risks. The ointment is marketed as a “cure-all” for a range of eye disorders, including dry eyes, cataracts, glaucoma, and styes, but the FDA has determined it is not safe for use. According to the FDA, Delsam Pharma's Artificial Eye Ointment contains two ingredients – trolamine and procaine hydrochloride – which have not been approved by the FDA for any medical use. These ingredients could cause serious side effects such as headache, confusion, mental changes, seizures, or difficulty breathing. Additionally, the product has not undergone any testing for safety or efficacy. The FDA urges consumers to immediately stop using Delsam Pharma's Artificial Eye Ointment and dispose of any remaining ointment. Consumers should also contact their healthcare provider if they have experienced any side effects from using the ointment. Consumers should be aware that not all products sold as “cure-alls” are safe or effective. The FDA recommends that people consult with their healthcare provider when considering the use of any health product, including eye ointments, in order to ensure they are using a safe and effective product. The U.S. Food and Drug Administration (FDA) has issued a warning to consumers to stop buying and using Delsam Pharma's Artificial Eye Ointment due to potentially serious health risks associated with the product. Marketed as a “cure-all” for a range of eye disorders, Delsam Pharma's Artificial Eye Ointment contains two ingredients – trolamine and procaine hydrochloride – that the FDA has determined are not safe for use. The FDA is concerned about the potential side effects of using Delsam Pharma's Artificial Eye Ointment, which include headache, confusion, mental changes, seizures, or difficulty breathing. Additionally, the product has not undergone any safety or efficacy testing, meaning that it is both potentially unsafe and ineffective. Passengers should immediately stop using Delsam Pharma's Artificial Eye Ointment and dispose of any remaining ointment. They should also contact their healthcare provider if they have experienced any side effects from using the ointment. When considering the use of any health product, including eye ointments, it is important to consult with a healthcare provider in order to ensure it is safe and effective. Products marketed as “cure-alls” are not always as safe or as effective as they claim to be, and consumers should be aware of the risks associated with using them. The FDA has identified a number of products available online that are unsafe or fraudulent, and the agency continues to work to prevent the sale and distribution of these products. Consumers should always be sure to purchase medical products from a trusted source and read all instructions before use. In light of the FDA's warning, it is essential for consumers to stop buying and using Delsam Pharma's Artificial Eye Ointment. This product has been found to contain two ingredients – trolamine and procaine hydrochloride – with potential serious health risks. Additionally, the product has not undergone any safety or efficacy testing, and consumers should be aware of the risks associated with it. If consumers have experienced any side effects while using Delsam Pharma's Artificial Eye Ointment, they should contact their healthcare provider immediately. Furthermore, consumers should be sure to consult with their healthcare provider before using any health product and read all instructions provided. The FDA also urges consumers to purchase medical products from a trusted source in order to ensure safety and efficacy. The FDA is committed to protecting the health and safety of consumers, and it aims to prevent the sale and distribution of unsafe or fraudulent products online. With the agency's warning to stop buying or using Delsam Pharma's Artificial Eye Ointment, consumers should be aware of the potential health risks associated with this product, as well as the risks associated with using products marketed as “cure-alls”.

https://www.lifetechnology.com/blogs/life-technology-medical-news/fda-widens-warning-for-contaminated-eye-products

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Pandemic created life-long risks for children in temporary accommodation in London, finds research

Adverse Impacts of the COVID-19 Pandemic on Children Under Five Living in Temporary Accommodation in London The COVID-19 pandemic has had a drastic impact on the lives of those living in temporary accommodation in London, especially on those aged under five. A recent study conducted by UCL researchers has revealed that there could be serious long-term implications as a result of the pandemic for these vulnerable children and their families. The research suggests that the pandemic has exacerbated existing social disadvantages for these children and their families, and that the awareness of the effects must be raised in order to inform future policy decisions. Background Temporary accommodation in London is a lifeline for many families in the city, particularly those who are homeless or have to move frequently due to financial problems or overcrowding. The most vulnerable among them are young children, who are particularly at risk of poor physical, mental and emotional health and poor educational outcomes. The COVID-19 pandemic has had a profound impact on the lives of those living in temporary accommodation in London, including vulnerable children below the age of five. This report aims to provide an overview of the effects of the pandemic on these children and their families, and to consider the implications of the pandemic for their future. Findings The research project surveyed parents of 129 children under the age of five living in temporary accommodation in London. The survey revealed that more than a third of the parents reported an adverse impact on the mental health and wellbeing of their children as a result of the pandemic. These impacts included stress, anxiety, and nightmares. In addition, more than a quarter of the parents reported that their children had become more withdrawn and had become negative about social interaction. The survey also indicated that the pandemic had caused financial hardship for families. Nearly two-thirds (64%) reported financial difficulties as a result of the pandemic, with some having to borrow or use food banks to survive. The survey also revealed that the pandemic had led to fewer opportunities for social interaction, with many parents feeling isolated. The research also looked at the impact of the pandemic on early childhood education. Over half of the parents (59%) reported that their children’s educational progress had been affected by the pandemic. These effects included lost educational opportunities, reduced access to early years services, and disruption of schooling. Implications and Future Policy Decisions The findings of this report suggest that the COVID-19 pandemic has adversely impacted the lives of young children living in temporary accommodation in London, and that these effects could have lasting implications for them. The findings also suggest that the pandemic has exacerbated existing social disadvantage for these children and their families, and that the awareness of the effects must be raised in order to inform future policy decisions. The report recommends that further research is conducted in order to understand and address the negative effects of the pandemic on these vulnerable children. It also recommends that local, national and international policies are developed and implemented to ensure that these children and their families have access to the resources and support they need and that the long-term impacts of the pandemic are addressed. Conclusion The findings of this report suggest that the COVID-19 pandemic has had a profound impact on the lives of children under five living in temporary accommodation in London, including adverse effects on their physical, mental and emotional health, educational progress, and financial wellbeing. The research also indicates that these effects could have long-term implications for these vulnerable children and their families, and that more research needs to be conducted in order to inform future policy decisions. It is essential that the awareness of the effects of the pandemic is raised in order to ensure that these children and their families receive the support and resources they need to recover and thrive.

https://www.lifetechnology.com/blogs/life-technology-medical-news/pandemic-created-life-long-risks-for-children-in-temporary-accommodation-in-london-finds-research

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Enlarged heart tied to worse chronic kidney disease outcomes

Introduction Chronic kidney disease (CKD) is a condition that affects millions of people worldwide, with over 850,000 people in the United States affected by the condition alone. It is a debilitating and complex condition that is characterized by a gradual decline in kidney function and the development of one or more associated conditions, including anemia, high blood pressure, and an increased risk of cardiovascular disease. The prognosis for people with CKD is highly variable and depends largely on the degree of kidney dysfunction, comorbid factors, and other factors. A recent study published in Communications Medicine examined the prognostic value of the cardiothoracic ratio (CTR) in people with CKD. What is the Cardiothoracic Ratio (CTR) The cardiothoracic ratio (CTR) is a measure of the ratio between the width of the heart and the width of the chest cavity at the level of the body’s widest point. It is typically measured in the anteroposterior (AP) view of a chest radiograph (chest x-ray). It is used to identify the presence and severity of certain types of heart and thoracic conditions. In particular, a high CTR is commonly associated with an enlarged heart, heart failure, and other cardiovascular diseases. Prognostic Value of the Cardiothoracic Ratio in CKD The recent study published in Communications Medicine examined the prognostic value of the cardiothoracic ratio in people with CKD. The study included a total of 474 CKD patients from a tertiary hospital in China. The patients underwent a chest x-ray and were followed-up for an average of 24.3 months. The study found that a higher CTR was associated with an increased risk of death in CKD patients. Specifically, the study found that CKD patients with a CTR of 0.7 or higher had a 54.7% higher risk of mortality compared to those with a CTR of 0.6 or less. Implications of the Study The findings of this study suggest that the cardiothoracic ratio (CTR) may have prognostic value for chronic kidney disease (CKD). The study suggests that a higher CTR may be associated with an increased risk of death in CKD patients. It is important to note, however, that the study was conducted in a single hospital in China and therefore may not be generalizable to other populations. Nevertheless, the findings of this study suggest that CTR may be a useful predictor of mortality in people with CKD and should be further explored. Conclusion Chronic kidney disease (CKD) is a debilitating and complex condition that is characterized by a gradual decline in kidney function and the development of one or more associated conditions. A recent study published in Communications Medicine examined the prognostic value of the cardiothoracic ratio (CTR) in people with CKD. The study found that a higher CTR was associated with an increased risk of death in CKD patients. The findings of this study suggest that the cardiothoracic ratio (CTR) may have prognostic value for chronic kidney disease (CKD) and should be further explored in order to better understand the underlying mechanisms. Further research is needed in order to further investigate the role of CTR in the prognosis of CKD patients.

https://www.lifetechnology.com/blogs/life-technology-medical-news/enlarged-heart-tied-to-worse-chronic-kidney-disease-outcomes

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Study: Trauma causes high levels of intergenerational substance use among Black women

Introduction Substance use disorders (SUDs) have become increasingly prevalent in the United States, with approximately 7.2 million women suffering from a SUD. A recent study has suggested that high levels of intergenerational substance use among Black women may be partly attributed to trauma. With this in mind, research from Penn State and the University of Kentucky has explored the role race and gender may play in this issue. In this article, we will discuss the findings of the research and look at ways to address the issue at hand. Study Findings on Intergenerational Substance Use Among Black Women The research team from Penn State and the University of Kentucky conducted two studies to look at the relationship between trauma and intergenerational substance use among Black women. The first study was a qualitative study that involved interviews with 24 Black women aged 18-60 who had a history of substance use. The second study was a quantitative study that surveyed 104 Black women aged 18-35 who had a history of substance use. The results of the study showed that trauma was a significant predictor of intergenerational substance use among Black women. Specifically, the study found that individuals who had experienced trauma were more likely to have higher levels of substance use than individuals who had not experienced trauma. Additionally, the study found that race and gender may also play a role in intergenerational substance use among Black women. Specifically, the results showed that Black women were more likely to engage in substance use than white women, even when accounting for differences in trauma exposure. Conclusion Substance use disorders (SUDs) are an increasingly prevalent issue in the United States, particularly among women. Recent research has suggested that trauma may be a major contributor to intergenerational substance use among Black women, and that race and gender may also have a role to play. Through its two studies, the research team from Penn State and the University of Kentucky has provided valuable insight into the role of trauma, race, and gender in this issue. Addressing the issue of intergenerational substance use in Black women will require a comprehensive approach that takes into account the social and cultural factors that are at play. This could include providing support for individuals who have experienced trauma, creating campaigns to raise awareness of the issue, and implementing social programs that seek to reduce the disparities between Black women and their white counterparts when it comes to access to healthcare and other resources. Keywords: Substance Use Disorders, Trauma, Black Women, Intergenerational Substance Use, Penn State, University of Kentucky

https://www.lifetechnology.com/blogs/life-technology-medical-news/study-trauma-causes-high-levels-of-intergenerational-substance-use-among-black-women

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Rectal pill may give days-long protection against HIV: Study

Is a Quick-Dissolving Pill in the Rectum an Effective and Safe Way to Prevent HIV Infection? In recent years, the medical community has made great strides in the fight against HIV infection. While preventative measures such as antiretroviral therapy (ART) and pre-exposure prophylaxis (PrEP) have been proven to be effective, there remains a need for additional methods that can help protect against the virus without the need for daily medication. An innovative new approach to HIV prevention involves quick-dissolving pills that are placed in the rectum. While the concept may seem unorthodox to some, it has the potential to be a safe, effective, and easy-to-use "on-demand" method of HIV prevention. The concept of rectally administered pill-based HIV prevention has been around since the 1990s, but only recently has it been studied in depth. Studies have demonstrated that the rectal mucosa is highly permeable to medications, and that the rectal lining can rapidly absorb the active ingredients with no long-term side effects. Additionally, the pill's enteric coating ensures that it dissolves quickly in the rectum, allowing rapid absorption of the active ingredients. The concept of a rectally administered pill for HIV prevention is promising and is currently being studied in clinical trials. The pill, called LY01, is a combination of four antiretroviral medications, including tenofovir, emtricitabine, rilpivirine, and a booster called cobicistat. These four drugs work together to block HIV from establishing an infection, and can be taken shortly before sex to provide protection for up to 72 hours. The pill's developers cite a number of potential benefits to its use, including convenience, lack of drug interactions, and improved adherence to treatment (since it is taken only on an as-needed basis). Additionally, it offers an alternative to traditional forms of HIV prevention such as PrEP, which requires daily medication, or condoms, which can be unreliable or cause discomfort. Despite the promise of the rectal pill-based HIV prevention, numerous questions remain. Currently, there is limited data available on the safety and effectiveness of the rectal pill in humans. Additionally, there is insufficient data on how the pill will interact with other drugs, such as recreational drugs or those used to treat existing HIV infections. It is also unclear how long the pill will remain in the rectum and whether it will be effective with repeated uses. Overall, the concept of a rectal pill for HIV prevention offers an attractive alternative to traditional modes of prevention, and is currently being studied in clinical trials. By providing a safe and effective means of HIV prevention, the pill may one day be an important piece of the puzzle in preventing HIV transmission. While more research is needed to determine its safety and efficacy, the pill's developers are optimistic about its potential to help reduce the spread of HIV.

https://www.lifetechnology.com/blogs/life-technology-medical-news/rectal-pill-may-give-days-long-protection-against-hiv-study

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Changing up your fitness routine could help maximize results

Introduction: Working out and exercising is a crucial part of staying healthy and staying in shape. However, it’s important to remember that different exercises are needed to reach different goals. It is also essential to keep up with a structured, consistent workout routine in order to achieve the desired results. However, the same workout routine performed over and over again can lead to a plateau in one’s training. It’s important to mix things up and find innovative ways to switch up your routine to keep seeing progress. The Benefits of Having a Structured Workout Routine When it comes to getting the most out of your workout, having a structured and consistent routine can have a big impact. Structured workout routines help to ensure that exercises are completed at a specific time, without interruption or distraction. This allows one to focus on the task at hand and optimise their performance. Structured work outs also help to track progression and results, allowing one to better understand how their routine is benefitting them. Additionally, structured workouts require fewer decisions and less thought, making it easier to stay motivated and actually complete the workouts. The Drawbacks of Sticking to the Same Workout Routine Too Long Sticking to the same workout routine for a long period of time can lead to a plateau in one’s progress. The body eventually reaches a point where it is no longer being challenged by the routine, leading to a decrease in progress and results. In addition to this, performing the same routine for too long can lead to boredom and lack of motivation. It’s important to mix things up and challenge the body in different ways in order to continue seeing progress. Tips for Mixing Up Your Workout Routine In order to keep seeing progress, it is important to mix things up and find innovative ways to switch up your workout routine. Here are some tips to help you get started: 1. Change up your exercises: Instead of doing the same exercises each workout, try to switch it up by focusing on different areas of your body or trying out completely different exercises. This will challenge your body in different ways and help you to see progress. 2. Increase intensity or duration: If you’re comfortable with the intensity or duration of your workout, try to increase them. This will push your body even further and help you to see greater results. 3. Have a workout partner: Having a workout partner can help to keep you motivated and engaged. Together, you can keep each other accountable and come up with innovative ideas to mix up your workout routine. 4. Try something new: Doing something you’ve never done before is a great way to keep your workout feeling fresh. Join a new class or try out a new machine at the gym. This will not only help to keep things interesting, but also add a new challenge for your body. Conclusion Having a structured and consistent workout routine is essential for achieving desired results and can help to keep one motivated and on track. However, it is important to remember to switch things up and not stick to the same routine for too long. Mixing up the routine can help to keep things interesting while challenging the body in different ways and leading to greater results. Taking the tips mentioned above into consideration can help to make sure you’re getting the most out of every workout and continuing to see progress.

https://www.lifetechnology.com/blogs/life-technology-medical-news/changing-up-your-fitness-routine-could-help-maximize-results

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'Cell food' gives insight into T cell metabolism

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https://www.lifetechnology.com/blogs/life-technology-medical-news/cell-food-gives-insight-into-t-cell-metabolism-1

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The era of globalization isn't over, new study argues

Reports of globalization's death are premature, according to a new study by researchers at the University of Waterloo, the University of British Columbia and the China Europe International Business School in Shanghai.

https://www.lifetechnology.com/blogs/life-technology-science-news/the-era-of-globalization-isnt-over-new-study-argues

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European big cat population threatened with extinction as genetics show the population is near collapse

Scientists warn that if action isn't taken soon, the Eurasian lynx will vanish from France. This elusive wild cat, which was reintroduced to Switzerland in the 1970s, moved across the French border by the end of the decade. But a genetic study published in Frontiers in Conservation Science showed that the lynx population in France is in desperate need of help to survive.

https://www.lifetechnology.com/blogs/life-technology-science-news/european-big-cat-population-threatened-with-extinction-as-genetics-show-the-population-is-near-collapse

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New study reveals pregnant people who deliver large babies are at increased risk of developing diabetes later in life

In a new study to be presented today at the Society for Maternal-Fetal Medicine's (SMFM) annual meeting, The Pregnancy Meeting—and published in the American Journal of Obstetrics and Gynecology—researchers will unveil findings that suggest pregnant people who do not have diabetes but deliver a large-for-gestational age baby are at an increased risk of developing prediabetes or Type 2 diabetes 10-14 years later.
https://www.lifetechnology.com/blogs/life-technology-medical-news/new-study-reveals-pregnant-people-who-deliver-large-babies-are-at-increased-risk-of-developing-diabetes-later-in-life

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Antibody properties in plasma can predict COVID-19 severity

Alterations in the biochemical makeup of bulk plasma IgG, or Fc glycosylation, can predict COVID-19 disease severity and vaccine antibody response, according to a recent study by researchers at RUSH University and Northwestern. The results of the study were recently published in Cell Reports.
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The convergence of epigenetics and math to predict and intercept cancer cell behavior

It is now widely understood that cancer is a disease of acquired defects in genes and gene function. An article published Feb. 9 in Science, and authored by Andrew Feinberg, M.D., of the Johns Hopkins Kimmel Cancer Center and the Institute for Basic Biomedical Sciences (IBBS) and Andre Levchenko, Sc.D., M.S., of the Yale School of Engineering and Applied Science, addresses new quantitative approaches to better define and measure these defects in gene function, known as epigenetics, and their interplay with the genetic landscape of cancer.
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